What is the inherited endocrine disorder that includes type 1 and type 2 syndromes affecting multiple glands?

The selected answer pertains to Multiple Endocrine Neoplasia (MEN-1), which is indeed an inherited condition characterized by tumors in multiple endocrine glands. This syndrome is categorized primarily into two types, MEN-1 and MEN-2, each associated with a distinct set of endocrine neoplasms affecting various glands like the pituitary, parathyroids, and pancreas in MEN-1, and thyroid and adrenal glands in MEN-2.

MEN-1 is particularly notable for causing pituitary adenomas, hyperparathyroidism due to parathyroid gland hyperplasia, and neuroendocrine tumors of the pancreas, which lead to hormone overproduction. The genetic basis of MEN syndromes involves mutations in tumor suppressor genes, which highlight the importance of hereditary factors in these disorders, ultimately influencing the development of neoplasms in multiple glands.

Other conditions mentioned in the options do not encompass the same broad spectrum of glandular involvement characteristic of MEN syndromes. For instance, Graves' disease primarily affects the thyroid and is an autoimmune disorder leading to hyperthyroidism, while Cushing's syndrome is a hypercortisolism condition originating from different sources, and hyperparathyroidism is a condition that can be caused by MEN-1 but is not