Which genetic syndrome is characterized by tumors or cysts that may be malignant or benign?

Von Hippel-Lindau syndrome is a genetic condition that is known for the development of various types of tumors and cysts, some of which can be malignant while others may be benign. This syndrome is associated with a predisposition to several types of tumors, including hemangioblastomas of the retina and central nervous system, renal cell carcinoma, and pheochromocytomas. Additionally, individuals with this syndrome often develop cysts in the kidneys and pancreas.

Understanding this syndrome is important because the presence of both benign and malignant lesions requires ongoing surveillance and management to catch potential malignancies early on. This distinguishes it from other conditions listed, which do not have the same broad spectrum of tumor risk or the specific combination of tumors and cysts. For instance, while neurofibromatosis does involve tumors, they are primarily neurofibromas that are typically benign. Marfan syndrome is primarily associated with connective tissue abnormalities rather than tumors, and Turner syndrome is characterized by a chromosomal condition affecting females, involving developmental concerns, but not specifically tumor formation.